Thursday 31 October 2019

New connections between chronic inflammatory disease, blood coagulation and cardiovascular degeneration


A study by Dr Ali Ethaeb in the Biomedical Section has been published in the journal Apoptosis. This study has established an essential connection between the inflammatory response, namely the release of initiator of blood coagulation “Tissue Factor” and the dysfunction of the coronary arterial endothelium. Ali Ethaeb obtained his PhD in 2018 from University of Hull and is currently working as a lecturer in University of Wasit, Republic of Iraq. As part of a larger group of PhD students Ali Ethaeb, Mohammad Mohammad, Sophie Featherby and Yahya Madkhali have studied the molecular and cellular mechanisms by which the elevation of Tissue Factor levels during chronic diseases such as cancer, diabetes and cardiovascular disease can cause endothelial cell death and denudation. The study is part of a lesser-extolled research endeavour which has been a long-running scientific program at Biomedical Sciences, spanning almost two decades and producing numerous peer-reviewed publications.

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